Johns Hopkins University: A Marker Indicates a 60% Likelihood of Developing Dementia

New research from the Johns Hopkins University School of Medicine has confirmed that muscle loss, known as “sarcopenia,” increases the risk of developing dementia. As a result, it is essential to “evaluate” muscular changes in older adults to determine appropriate treatment options.

The study focused on the jaw muscle, which may reflect overall muscle mass in the body. Dr. Marilyn Albert, a neurology professor, stated, “Older adults with smaller muscle mass are 60% more likely to develop dementia, as the body begins losing 3% to 5% of muscle mass every decade after the age of 30.”

While the link between sarcopenia and cognitive decline is not fully understood, researchers attribute the cause to the effects of myokines—substances produced by muscles that influence the brain. These effects must be addressed through two critical approaches: “exercise and participation in social activities” combined.

The researchers also recommended assessing muscular changes during brain exams for older adults. This suggestion came after reviewing brain images of 621 seniors without dementia. In addition to the importance of exercise and social engagement, the study emphasized following “dietary guidelines.”